About us
Leducq Foundation’s PRIORITY network
The PRIORITY project—short for cardio-laminoPathy: fRom pathomechanIsms tO peRsonalIzed TherapY—is a major international research initiative funded by the Leducq Foundation with an $8 million grant. Launched in January 2025, it focuses on LMNA-related dilated cardiomyopathy (LMNA-DCM), a severe hereditary heart condition caused by mutations in the LMNA gene. These mutations disrupt the structure and function of the cell nucleus, leading to progressive heart failure and arrhythmias. (fondationleducq.org, LMNA Cardiac, institut-myologie.org)
Leducq Foundation’s PRIORITY network
Coordinators
Prof. Dr. Gisèle Bonne – Sorbonne Université, INSERM, France
Prof. Dr. Andrew Landstrom – Duke University School of Medicine, USA
Principal Members
Prof. Dr. Jan Lammerding – Cornell University, USA
Prof. Dr. Haiyuan Yu – Cornell University, USA
Prof. Dr. Mark Mercola – Stanford University, USA
Dr. Ioannis Karakikes – Stanford University, USA
Prof. Dr. Yigal Pinto – Netherlands Heart Institute – Amsterdam UMC, the Netherlands
Dr. Rogier Veltrop – Netherlands Heart Institute – Maastricht UMC, the Netherlands
Prof. Dr. Karim Wahbi – Paris-Cité University, France
Prof. Dr. Ohad Medalia – Unversity of Zurich, Switzerland
Partner Institutions
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Sorbonne Université / INSERM (France)
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Duke University School of Medicine (USA)
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Netherlands Heart Institute (Netherlands)
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Cornell University (USA)
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Paris-Cité University (France)
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Stanford University (USA)
