About us
Leducq Foundation’s PRIORITY network
The PRIORITY project—short for cardio-laminoPathy: fRom pathomechanIsms tO peRsonalIzed TherapY—is a major international research initiative funded by the Leducq Foundation with an $8 million grant. Launched in January 2025, it focuses on LMNA-related dilated cardiomyopathy (LMNA-DCM), a severe hereditary heart condition caused by mutations in the LMNA gene. These mutations disrupt the structure and function of the cell nucleus, leading to progressive heart failure and arrhythmias. (fondationleducq.org, LMNA Cardiac, institut-myologie.org)
Leducq Foundation’s PRIORITY network
Coordinators
Dr. Gisèle Bonne – Sorbonne Université, INSERM, France
Dr. Andrew Landstrom – Duke University School of Medicine, USA
Principal Members and Institutions
Dr. Yigal Pinto – Netherlands Heart Institute, Netherlands
Dr. Leon Schurgers – Netherlands Heart Institute, Netherlands
Dr. Haiyuan Yu – Cornell University, USA
Dr. Jan Lammerding – Cornell University, USA
Dr. Karim Wahbi – Paris-Cité University, France
Dr. Mark Mercola – Stanford University, USA
Dr. Ioannis Karakikes – Stanford University, USA
Partner Institutions
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Sorbonne Université / INSERM (France)
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Duke University School of Medicine (USA)
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Netherlands Heart Institute (Netherlands)
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Cornell University (USA)
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Paris-Cité University (France)
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Stanford University (USA)
